Marco M Gottardis Selected Research

BMS-554417

9/2008

HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Marco M Gottardis Research Topics

Disease

19	Neoplasms (Cancer) 01/2021 - 03/2003
12	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 10/2005
9	Breast Neoplasms (Breast Cancer) 03/2012 - 06/2006
4	Rhabdomyosarcoma 11/2010 - 01/2009
3	Sarcoma (Soft Tissue Sarcoma) 11/2010 - 01/2009
2	Leukemia 09/2012 - 12/2009
2	Neoplasm Metastasis (Metastasis) 03/2012 - 01/2012
2	Neuroblastoma 12/2009 - 01/2009
1	Adenocarcinoma 01/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/2012
1	Triple Negative Breast Neoplasms 04/2011
1	Resistance To Insulin-Like Growth Factor I 09/2010
1	Carcinoid Tumor (Carcinoid) 09/2010
1	Type 2 Diabetes Mellitus (MODY) 01/2010
1	Liposarcoma 12/2009
1	Multiple Myeloma 12/2009
1	Ovarian Epithelial Carcinoma 11/2009
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2009
1	Ovarian Neoplasms (Ovarian Cancer) 09/2008
1	Febrile Neutropenia 06/2007
1	Diarrhea 06/2007
1	Carcinoma (Carcinomatosis) 06/2007
1	Sepsis (Septicemia) 06/2007
1	Leiomyosarcoma 06/2007
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 06/2006

Drug/Important Bio-Agent (IBA)

9	BMS 536924IBA 09/2012 - 09/2008
7	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 10/2005
6	BMS 754807IBA 01/2012 - 12/2009
6	Hormones (Hormone)IBA 12/2011 - 10/2005
5	Insulin ReceptorIBA 09/2012 - 09/2008
5	Tyrosine Kinase InhibitorsIBA 09/2012 - 01/2009
4	AndrogensIBA 01/2021 - 06/2006
4	Phosphotransferases (Kinase)IBA 09/2012 - 09/2010
4	Insulin-Like PeptidesIBA 12/2011 - 01/2011
4	AntibodiesIBA 04/2011 - 09/2010
4	IGF Type 1 Receptor (IGF 1 Receptor)IBA 02/2011 - 01/2009
3	LigandsIBA 01/2021 - 03/2003
3	Insulin (Novolin)FDA Link 01/2012 - 01/2010
2	Androgen Receptor AntagonistsIBA 01/2021 - 01/2021
2	benzimidazoleIBA 01/2016 - 01/2011
2	Proteins (Proteins, Gene)FDA Link 03/2012 - 01/2011
2	Estrogens (Estrogen)FDA Link 12/2011 - 06/2006
2	Insulin-Like Growth Factor I (IGF-1)IBA 04/2011 - 09/2008
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2011 - 11/2010
2	Biological ProductsIBA 01/2011 - 03/2003
2	Somatomedin Receptors (Somatomedin Receptor)IBA 01/2011 - 01/2009
2	Pharmaceutical PreparationsIBA 01/2011 - 11/2010
2	Biomarkers (Surrogate Marker)IBA 09/2010 - 01/2009
1	AntigensIBA 01/2022
1	JNJ-63576253IBA 01/2021
1	LyasesIBA 01/2016
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2016
1	compound 18IBA 01/2016
1	Cre recombinaseIBA 09/2012
1	Tyrosine (L-Tyrosine)FDA Link 09/2012
1	Insulin-Like Growth Factor Binding ProteinsIBA 03/2012
1	Insulin-Like Growth Factor Binding Protein 5IBA 03/2012
1	Insulin-Like Growth Factor Binding Protein 4IBA 03/2012
1	src-Family KinasesIBA 01/2012
1	Dasatinib (BMS 354825)FDA Link 01/2012
1	Tamoxifen FDA LinkGeneric 12/2011
1	Antineoplastic Agents (Antineoplastics)IBA 12/2011
1	Letrozole (Femara)FDA LinkGeneric 12/2011
1	Docetaxel (Taxotere)FDA Link 04/2011
1	matrigelIBA 02/2011
1	Phenobarbital (Luminal)FDA Link 02/2011
1	Cetuximab (Erbitux)FDA Link 01/2011
1	Epidermal Growth Factor (EGF)IBA 01/2011
1	ErbB Receptors (EGF Receptor)IBA 01/2011
1	Fibronectins (Fibronectin)IBA 01/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011
1	Panitumumab (Vectibix)FDA Link 01/2011
1	nimotuzumabIBA 01/2011
1	Small Interfering RNA (siRNA)IBA 11/2010
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2010
1	Ribosomal Protein S6IBA 11/2010
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 09/2010
1	Transforming Growth Factor-beta Type I ReceptorIBA 09/2010
1	Glucose (Dextrose)FDA LinkGeneric 01/2010
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2009
1	Caspase 3 (Caspase-3)IBA 12/2009
1	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)IBA 12/2009
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 11/2009
1	3-aminobenzamideIBA 11/2009
1	bicalutamide (Casodex)FDA LinkGeneric 08/2009
1	Androgen Antagonists (Antiandrogens)IBA 08/2009
1	BMS 641988IBA 08/2009
1	BMS-554417IBA 09/2008
1	(4- ((1- (3- fluorophenyl)methyl)- 1H- indazol- 5- ylamino)- 5- methylpyrrolo(2,1- f)(1,2,4)triazin- 6- yl)carbamic acid 3-morpholinylmethyl esterIBA 09/2008
1	beta CateninIBA 01/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 06/2007
1	7- cyano- 2,3,4,5- tetrahydro- 1- (1H- imidazol- 4- ylmethyl)- 3- (phenylmethyl)- 4- (2- thienylsulfonyl)- 1H- 1,4- benzodiazepine (BMS 214662)IBA 06/2007
1	Transaminases (Aminotransferases)IBA 06/2007
1	Testosterone (Sustanon)FDA Link 10/2005

Therapy/Procedure

11	Therapeutics 01/2021 - 10/2005
7	Castration 01/2022 - 01/2008
1	Immunotherapy 01/2022
1	Oral Administration 01/2021
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 09/2012
1	Mammaplasty (Breast Reconstruction) 03/2012